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Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: Synergy of triple combination therapy on human airway smooth muscle ex vivo.

Rogliani PaolaMaria Gabriella MateraFrancesco FaccioloClive PageMario CazzolaLuigino Calzetta
Published in: British journal of pharmacology (2020)
Triple beclomethasone/formoterol/glycopyrronium combination induces synergistic bronchorelaxant effect in medium and small human airways, at least in ex vivo experiments. Further research is needed to confirm these findings in clinical studies in patients with asthma or COPD.
Keyphrases
  • smooth muscle
  • combination therapy
  • endothelial cells
  • chronic obstructive pulmonary disease
  • induced pluripotent stem cells
  • lung function
  • cystic fibrosis