Hepatic stellate cell as a Mac-2-binding protein-producing cell in patients with liver fibrosis.

Dolgormaa Gantumur Norifumi HarimotoRyo MuranushiKouki HoshinoChingun BatbayarKei HagiwaraTakahiro YamanakaNorihiro IshiiMariko TsukagoshiTakamichi IgarashiAkira WatanabeNorio KuboKenichiro ArakiTakehiko YokoboriShinichi AishimaKen Shirabe

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2021)

M2BP mRNA transcription in fibrotic liver was primarily observed in HSCs but not at the M2BP level, which suggests that HSCs might produce and introduce M2BP to Kupffer cells and serum.

Keyphrases

liver fibrosis
binding protein
single cell
cell therapy
induced apoptosis
transcription factor
systemic sclerosis
cell proliferation
mesenchymal stem cells