Interferon lambda 4 rs368234815 TT>δG variant is associated with liver damage in patients with nonalcoholic fatty liver disease.
Salvatore PettaLuca Vittorio ValentiAntonino TuttolomondoPaola DongiovanniRosaria Maria PipitoneCalogero CammàDaniela CabibiVito Di MarcoAnna Ludovica FracanzaniSara BadialiValerio NobiliSilvia FargionStefania GrimaudoAntonio CraxìPublished in: Hepatology (Baltimore, Md.) (2017)
The IFNL4 genotype is associated with severity of fibrosis in nonalcoholic fatty liver disease patients of European ancestry, likely by modulating the activation of innate immunity and necroinflammation. (Hepatology 2017;66:1885-1893).