4D Flow Patterns and Relative Pressure Distribution in a Left Ventricle Model by Shake-the-Box and Proper Orthogonal Decomposition Analysis.

Xiaolin WuHicham SaaidJason VoorneveldTom ClaessensJos J M WestenbergNico de JongJohan G BoschSaša Kenjereš

Published in: Cardiovascular engineering and technology (2023)

This work demonstrated Shake-the-Box is a promising technique to accurately reconstruct the left ventricle flow field in vitro. The good spatial and temporal resolutions of the velocity measurements enabled a 4D reconstruction of the pressure field in the left ventricle. The application of POD analysis showed its potential in reducing the complexity of the high-resolution left ventricle flow measurements. For future work, image analysis, multi-modality flow assessments, and the development of new flow-derived biomarkers can benefit from fast and data-reducing POD analysis.

Keyphrases

pulmonary artery
high resolution
pulmonary hypertension
mitral valve
transcription factor
binding protein
pulmonary arterial hypertension
electronic health record