Neurological Manifestations of Histiocytic Disorders.

Samantha A BanksJulio C Sartori ValinottiRonald S GoJithma P AbeykoonGaurav GoyalJason R YoungMatthew J KosterRobert VassalloJay H RyuCaroline J Davidge-PittsAishwarya RavindranN Nora BennaniMithun V ShahKaren L RechWilliam Oliver Tobinnull null

Published in: Current neurology and neuroscience reports (2023)

Recent advances in the treatment of these diseases targeted towards mutations in the MAP kinase pathway have led to an improved prognosis in these patients with neurologic involvement. It is critical for clinicians to have a high index of suspicion to allow for early targeted treatment and optimize neurologic outcomes. A systematic approach to diagnosis is presented in this article to allow for accurate diagnosis of these rare diseases.

Keyphrases

cancer therapy
type diabetes
high resolution
palliative care
combination therapy
tyrosine kinase
subarachnoid hemorrhage
insulin resistance
protein kinase
high density