Empiric antibiotics for community-acquired pneumonia in adult patients: a systematic review and a network meta-analysis.
Lara Montes-AndujarElena TinocoOrville Baez-PraviaCarlos Martin-SaboridoPablo Blanco-SchweizerCarmen SeguraEstefania Prol SilvaVivivan ReyesAna Rodriguez CoboCarmen ZurdoVerónica AngelOlga VaronaJosé ValeroRafael Suarez Del VillarGuillermo OrtizJulio VillanuevaJusto MenéndezJesús BlancoAntoni TorresPablo A Cardinal-FernándezPublished in: Thorax (2021)
For cure rate, ceftaroline and piperaciline are the options with the HPBB. However, for mortality rate, the options are ceftriaxone plus levofloxacin, ertapenem and amikacin plus clarithromycin. It seems necessary to conduct an RCT that compares treatments with the HPBB for each event (cure or mortality) (CRD42017060692).