Protection of coenzyme Q10 against contrast-induced acute kidney injury in male diabetic rats.

Sheila Marques Fernandes CoutoCassiane Dezoti da FonsecaMirian WatanabeMaria de Fátima Fernandes Vattimo

Published in: Diabetology & metabolic syndrome (2021)

This study demonstrated the renoprotection properties of CoQ10 in an experimental model of risk factor of DM for CI-AKI. CoQ10 presented an antioxidant effect on the CI-AKI in male diabetic rats by improving renal function and renal hemodynamics, preserving morphology and reducing oxidative stress.

Keyphrases

diabetic rats
oxidative stress
acute kidney injury
dna damage
risk factors
ischemia reperfusion injury
induced apoptosis
magnetic resonance
skeletal muscle
signaling pathway
weight loss
endothelial cells