Real-life use of BRAF-V600E mutation analysis in thyroid nodule fine needle aspiration: consequences on clinical decision-making.

Giulia BriganteAndrea CraparoElisa PignattiMarco MarinoMaria Laura Monzani Sara De Vincentis Livio Casarini Samantha SperdutiGisella BoselliGianluca MargiottaMargherita IppolitoVincenzo Rochira Manuela Simoni

Published in: Endocrine (2021)

The analysis of BRAF-V600E outside of gene panels has low sensitivity, especially in indeterminate nodules, and a positive result could lead to more extensive surgery with greater risk of hypoparathyroidism and questionable clinical utility.

Keyphrases

fine needle aspiration
ultrasound guided
decision making
minimally invasive
metastatic colorectal cancer
coronary artery bypass
copy number
genome wide
gene expression
surgical site infection
genome wide identification
acute coronary syndrome
percutaneous coronary intervention
atrial fibrillation