Pregnancy disrupts the accuracy of automated fT4 immunoassays.

Heleen I JansenAntonius E van HerwaardenHenk J HuijgenRebecca C PainterJacquelien J HillebrandAnita BoelenAnnemieke C Heijboer

Published in: European thyroid journal (2022)

Our results indicate that immunoassays overestimate fT4 in pregnant women, which might lead to an overestimation of thyroid status. Physicians and laboratory specialists should be aware of this phenomenon to avoid drawing false conclusions about thyroid function in pregnant women.

Keyphrases

pregnant women
pregnancy outcomes
primary care
machine learning
deep learning
preterm birth
high throughput