Genetic, Clinicopathological, and Radiological Features of Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation Pattern.

Taek Chung Hyungjin Rhee Hyo Sup Shim Jeong Eun Yoo Gi-Hong Choi Haeryoung Kim Young Nyun Park

Published in: Gut and liver (2021)

iCCAs with DPM pattern have different clinico-radio-pathologic and genetic characteristics compared to conventional iCCAs. Moreover, FGFR and ARID1A variants were identified. Altogether, these findings further suggest that iCCA with DPM pattern represents a specific subtype of small duct type iCCA.

Keyphrases

copy number
genome wide
dna methylation
radiation therapy
locally advanced