Serum matrix metalloproteinase-7: a potential biomarker in patients with Lynch Syndrome.
Doron YablecovitchHussein MahajnaNir HoreshEfraim KatzOrit PicardMiri YavzoriElla FudimTalia SakerShomron Ben-HorinIdo LaishPublished in: Molecular biology reports (2023)
Age-adjusted serum MMP-7 levels in asymptomatic LS carriers are higher than its levels in healthy population. While in colon cancer, MMP-7 higher level probably reflects the tumor burden and may have a prognostic effect, its significance and clinical applicability as a biomarker for tumorigenesis in LS is less clear and should be elucidated.
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