Influence of CYP2A6 genetic variation, nicotine dependence severity, and treatment on smoking cessation success.
Meghan J ChenowethCaryn LermanJoanne KnightRachel Fynvola TyndalePublished in: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2023)
Variation in CYP2A6 and nicotine dependence severity alter smoking cessation success. Our findings suggest that while nicotine dependence severity is unlikely to mediate or moderate CYP2A6 associations with cessation, incorporating patient information on both CYP2A6 and nicotine dependence severity may lead to improved smoking cessation strategies.