Neural substrates of predicting anhedonia symptoms in major depressive disorder via connectome-based modeling.

Tingyu YangYangpan OuHuabing LiFeng LiuPing LiGuangrong XieJingping ZhaoXilong CuiWen-Bin Guo

Published in: CNS neuroscience & therapeutics (2024)

This study successfully established a network model for predicting anhedonia symptoms in MDD based on FC, as well as a classification model to differentiate between melancholic and non-melancholic MDD patients. These findings provide guidance for clinical treatment.

Keyphrases

major depressive disorder
bipolar disorder
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
deep learning
prognostic factors
sleep quality
patient reported outcomes