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Combined Treatment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Endothelial Cells Regenerate the Infarcted Heart in Mice and Non-Human Primates.

Yu-Che ChengMarvin L HsiehChen-Ju LinCindy M C ChangChing-Ying HuangRiley PuntneyAmy Wu MoyChien-Yu TingDarien Zhing Herr ChanMartin W NicholsonPo-Ju LinHung-Chih ChenGina C KimJianhua ZhangJennifer CoonenPuja BasuHeather A SimmonsYen-Wen LiuTimothy A HackerTimothy J KampPatrick Ching-Ho Hsieh
Published in: Circulation (2023)
These results demonstrate the synergistic effect of combining iPSC-derived ECs and CMs for therapy in the postmyocardial infarction heart, enabling a promising strategy toward clinical translation.
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