Systematic review and evidence gap mapping of biomarkers associated with neurological manifestations in patients with COVID-19.

K Z A DominguesA F CobreR E L LazoL S AmaralL M FerreiraF S ToninRoberto Pontarolo

Published in: Journal of neurology (2023)

Different neurological biomarkers in neurosymptomatic COVID-19 patients were identified in observational studies. Although the evidence is still scarce and conflicting for some biomarkers, well-designed longitudinal studies should further explore the pathophysiological role of NfL, GFAP, and tau protein and their potential use for COVID-19 diagnosis and management.

Keyphrases

systematic review
sars cov
coronavirus disease
high resolution
meta analyses
cerebral ischemia
protein protein
binding protein
brain injury
small molecule
mass spectrometry
respiratory syndrome coronavirus
case control