TLR agonists promote formation of Tertiary Lymphoid Structure and improve anti-glioma immunity.
Shaoping ShenYong CuiMingxiao LiKefu YuQinghui ZhuXiaokang ZhangWeicheng ShenHaoyi LiHaihui JiangMing LiXijie WangXuzhe ZhaoXiaohui RenSong LinPublished in: Neuro-oncology (2024)
TLS induction in GME enhanced anti-glioma immunity, improved the immune microenvironment, and controlled glioma growth, suggesting potential therapeutic avenues for treating glioma in the future.