Effects of the neuroprotective drugs somatostatin and brimonidine on retinal cell models of diabetic retinopathy.

Elena BeltramoTatiana LopatinaAurora MazzeoAna I ArrobaAngela M ValverdeCristina HernándezRafael SimóMassimo Porta

Published in: Acta diabetologica (2016)

Retinal pericytes express SSTR1, indicating that they can be a target for SST. Exposure to SST/BRM had no adverse effects, direct or mediated by the neuroretina, suggesting that these molecules could be safely evaluated for the treatment of ocular diseases.

Keyphrases

diabetic retinopathy
optical coherence tomography
single cell
optic nerve
cell therapy
cerebral ischemia
mesenchymal stem cells
neuroendocrine tumors
replacement therapy