Efficacy and Toxicity Analysis of mFOLFIRINOX in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms.

Michele BorghesaniAnna ReniEleonora LauricellaAlice RossiViola MoscardaElena TrevisaniIrene TorresanTaymeyah Al-ToubahElisabetta FiloniClaudio LuchiniRiccardo De RobertisLuca LandoniAldo ScarpaCamillo PortaMichele MilellaJonathan StrosbergMauro CivesSara Cingarlini

Published in: Journal of the National Comprehensive Cancer Network : JNCCN (2024)

mFOLFIRINOX shows antitumor activity against high-grade NENs. Well-designed, prospective clinical trials are needed to assess the efficacy of mFOLFIRINOX in both the neoadjuvant and metastatic settings.

Keyphrases

high grade
low grade
clinical trial
squamous cell carcinoma
small cell lung cancer
rectal cancer
oxidative stress
locally advanced
radiation therapy