Mxc, a Drosophila homolog of mental retardation-associated gene NPAT, maintains neural stem cell fate.

Rong SangCheng WuShanshan XieXiao XuYuhan LouWanzhong GeYongmei XiXiaohang Yang

Published in: Cell & bioscience (2022)

Our study demonstrate that Mxc plays a critical role in maintaining neural stem cell fate and GMC differentiation in the Drosophila larval brain. This discovery may shed light on the understanding of the pathogenesis of NPAT-related mental retardation in humans.

Keyphrases

cell fate
mental health
small molecule
high throughput
white matter
genome wide
gene expression
resting state
zika virus
aedes aegypti
transcription factor
subarachnoid hemorrhage
drug induced