Effect of allergens and irritants on levels of natural moisturizing factor and corneocyte morphology.
Sjors A KoppesSuzana Ljubojević HadžavdićIvone JakasaNika FranceschiChristoph RiethmüllerRužica Jurakić TončicBranka MarinovicNidhin RajAnthony V RawlingsRainer VoegeliMajella E LaneMarek HaftekMonique H W Frings-DresenThomas RustemeyerSanja KezicPublished in: Contact dermatitis (2017)
MCI/MI significantly decreased NMF levels, similarly to SLS. The altered corneocyte morphology suggests that skin barrier damage plays a role in the pathogenesis of MCI/MI contact allergy. The DTI seems to differentiate reactions to SLS from those to the allergens tested, as SLS was the only agent that caused a DTI increase.