Duration of Postvaccination Neutralizing Antibodies to SARS-CoV-2 and Medication Effects: Results from the Safety and Immunogenicity of COVID-19 Vaccination in Systemic Immune-Mediated Inflammatory Diseases Cohort Study.
Rami HabibRoya M DayamCarol A HitchonVinod ChandranPaul R FortinGilles BoireDawn M E BowdishAnne-Claude GingrasLouis FlamandMaggie J LarchéGregory PrattLuck LukusaJennifer L F LeeDaniel PereiraCharles N BernsteinNadine LalondeElizabeth TurnbullSasha Bernatskynull nullPublished in: ACR open rheumatology (2024)
Neutralization responses in immunosuppressed individuals with IMID were durable over time and were augmented by more than three doses and Omicron-specific vaccines. Less neutralization was seen with certain medications. Our work clarifies the joint effects of vaccine history, infection, and medications on COVID-19 immunity.