Biopsy and blood-based molecular biomarker of inflammation in IBD.
Carmen A ArgmannRuixue HouRyan C UngaroHaritz IrizarZainab Al-TaieRuiqi HuangRoman KosoySwati VenkatWon-Min SongAntonio F Di NarzoBojan LosicKe HaoLauren PetersPhillip H ComellaGabrielle WeiAshish AtrejaMilind MahajanAlina IugaPrerak T DesaiPatrick BraniganAleksandar StojmirovicJacqueline PerrigoueCarrie BrodmerkelMark CurranJoshua R FriedmanAmy HartEsi Lamousé-SmithJan WehkampSaurabh MehandruEric E SchadtBruce E SandsMarla C DubinskyJean-Frederic ColombelAndrew KasarskisMayte Suárez-FariñasPublished in: Gut (2022)
Transcriptionally based scores provide an alternative objective and deeper quantification of intestinal inflammation, which could augment current clinical assessments used for disease monitoring and have potential for predicting therapeutic response and patients at higher risk of disease flares.