TSPAN8 regulates EGFR/AKT pathway to enhance metastasis in gastric cancer.

Lin ZhangYuting XuEnmin CaiMaojin ZhengLei LiuQingling WangShibao Li

Published in: Molecular biology reports (2023)

Our study reveals that TSPAN8 plays a significant role in promoting tumor metastasis by activating the EGFR/AKT pathway, indicating that it may serve as a promising therapeutic target of gastric cancer.

Keyphrases

signaling pathway
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
cell proliferation