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Brucine Inhibits Proliferation of Pancreatic Ductal Adenocarcinoma through PI3K/AKT Pathway-induced Mitochondrial Apoptosis.

Yiqi DuFenglin ZhangPanling XuPing Li
Published in: Current cancer drug targets (2024)
Overall, these findings suggest that brucine has therapeutic potential as a remedy option for PDAC.
Keyphrases
  • oxidative stress
  • diabetic rats
  • high glucose
  • endoplasmic reticulum stress
  • cell cycle arrest
  • cell death
  • drug induced
  • endothelial cells
  • cell proliferation
  • signaling pathway