Early buprenorphine-naloxone initiation for opioid use disorder reduces opioid overdose, emergency room visits and healthcare cost compare to late initiation.
Tianyu SunHilary ArokeStephen KogutNatallia KatenkaJeffrey P BratbergAshley BuchananPublished in: The American journal of drug and alcohol abuse (2021)
Compared to late BUP-NX initiation, early initiation was associated with a lower risk of opioid overdose and opioid overdose-related ED visits, and reduced total healthcare cost among insured adult patients with OUD.