Directed C8-H allylation of quinoline N -oxides with vinylcyclopropanes via sequential C-H/C-C activation.

The Rh(III)-catalyzed C8-allylation of quinoline N -oxides has been accomplished using vinylcyclopropanes as an allyl source with excellent diastereoselectivity at room temperature. The C-H/C-C activation, substrate scope and natural product mutation are the important practical features.