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Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes.

Seyit Ali GumustasIbrahim YilmazMehmet IsyarDuygu Yasar SirinAhmet Guray BatmazAli Akin UgrasKadir OznamZafer CiftciMahir Mahirogullari
Published in: Journal of orthopaedic surgery and research (2016)
Before administering phenyl alkanoic acid derivatives in the clinical setting, their role in suppressing the proliferation and differentiation of chondrocytes should be taken into account. Thus, caution should be given when prescribing these drugs.
Keyphrases
  • signaling pathway
  • primary care
  • chronic pain
  • oxidative stress
  • extracellular matrix
  • pain management
  • adverse drug
  • spinal cord