Magnetic field distribution modulation of intrathecal delivered ketorolac iron-oxide nanoparticle conjugates produce excellent analgesia for chronic inflammatory pain.

Ping-Ching WuDar-Bin ShiehHung-Tsung HsiaoJeffery Chi-Fei WangYa-Chi LinYen-Chin Liu

Published in: Journal of nanobiotechnology (2018)

Our results indicated that intrathecal administration of the Keto-SPIO combined magnet field modulated delivery significantly promoted an analgesia effect with suppression of COX in the mice inflammatory pain model.

Keyphrases

pain management
iron oxide
chronic pain
postoperative pain
neuropathic pain
oxidative stress
ultrasound guided
spinal cord
type diabetes
metabolic syndrome
cancer therapy
spinal cord injury
adipose tissue
wild type