Significance of "de novo" appearance of thyroglobulin antibodies in patients with differentiated thyroid cancer.
Lorenzo ScappaticcioPierpaolo TrimboliFrederik A VerburgLuca GiovanellaPublished in: The International journal of biological markers (2020)
Transient de novo TgAbs appearance is not infrequent during DTC patients' follow-up, and it has no apparent clinical impact. Sustained de novo TgAbs appearance is rare and may predict structural recurrences; however, similar disease-free survival was observed in patients with sustained de novo TgAbs and TgAb-negative DTC patients.