Pharmacogenetics in Oncology: A useful tool for individualizing drug therapy.
Rita Nogueiras-ÁlvarezInés Pérez FranciscoPublished in: British journal of clinical pharmacology (2024)
With the continuous development of genetics in healthcare, there has been a significant contribution to the development of precision medicine, which is ultimately aimed at improving the care of patients. Generally, drug treatments used in Oncology are characterized by a narrow therapeutic range and by their potential toxicity. Knowledge of pharmacogenomics and pharmacogenetics can be very useful in the area of Oncology, as they constitute additional tools that can help to individualize patients' treatment. This work includes a description of some genes that have been revealed to be useful in the field of Oncology, as they play a role in drug prescription and in the prediction of treatment response.
Keyphrases
- healthcare
- palliative care
- end stage renal disease
- ejection fraction
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- emergency department
- stem cells
- gene expression
- adverse drug
- genome wide
- risk assessment
- dna methylation
- social media
- climate change
- electronic health record
- smoking cessation
- combination therapy
- human health
- genome wide analysis