The antinociceptive effect of resveratrol in bone cancer pain is inhibited by the Silent Information Regulator 1 inhibitor selisistat.
Sebastian LuxNicolas LobosCarolyne Lespay-RebolledoEdison Salas-HuenuleoMarcelo J KoganChristian FloresMauricio PintoAlejandro HernandezTeresa PelissierLuis ConstandilPublished in: The Journal of pharmacy and pharmacology (2018)
Acute and chronic resveratrol induces antinociceptive effect in the model of metastatic osseous oncological pain, an effect that would be mediated by SIRT1 molecular signalling.
Keyphrases
- chronic pain
- pain management
- neuropathic pain
- squamous cell carcinoma
- small cell lung cancer
- liver failure
- prostate cancer
- papillary thyroid
- anti inflammatory
- transcription factor
- drug induced
- bone mineral density
- intensive care unit
- spinal cord
- postmenopausal women
- body composition
- squamous cell
- radical prostatectomy
- lymph node metastasis
- extracorporeal membrane oxygenation