Frailty is characterized by biomarker patterns reflecting inflammation or muscle catabolism in multi-morbid patients.

Bastian KochlikKristina FranzThorsten HenningDaniela WeberAndreas WernitzCatrin HerpichFranziska JannaschVolkan AykaçUrsula Müller-WerdanMatthias B SchulzeTilman GruneKristina Norman

Published in: Journal of cachexia, sarcopenia and muscle (2022)

We conclude that two specific patterns reflecting either inflammation-related or muscle-related biomarkers are both significantly associated with frailty among multi-morbid patients and that these specific biomarker patterns are more informative than single biomarker analyses considering frailty identification.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
oxidative stress
prognostic factors
bariatric surgery
skeletal muscle
patient reported outcomes
community dwelling