Reduced congestion and improved response to a fluid/sodium challenge in chronic heart failure patients after initiation of sacubitril/valsartan: The NATRIUM-HF study.

Alexandre MebazaaBeth A DavisonJan BiegusChristopher EdwardsGillian MurtaghChristos VarounisHamlet HayrapetyanHamayak SisakianVictor R Ter-GrigoryanKoji TakagiMaria NovosadovaPiotr PonikowskiGad Cotter

Published in: European journal of heart failure (2024)

The initiation of sacubitril/valsartan in HFrEF patients was associated with improvements in natriuresis, diuresis, and weight loss and better clinical adaptation to potentially decongestive stressors.

Keyphrases

ejection fraction
weight loss
end stage renal disease
chronic kidney disease
newly diagnosed
bariatric surgery
peritoneal dialysis
prognostic factors
patient reported outcomes
skeletal muscle
body mass index
roux en y gastric bypass
obese patients