Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C.

Masaru Enomoto Yoshihiro IkuraAkihiro TamoriRitsuzo KozukaHiroyuki MotoyamaEtsushi KawamuraAtsushi HagiharaHideki FujiiSawako Uchida-KobayashiHiroyasu MorikawaYoshiki MurakamiNorifumi Kawada

Published in: United European gastroenterology journal (2018)

Even if transaminases become normal after obtaining a sustained virologic response, significant histological inflammation of unknown cause was found in some patients. Additionally, improvement in liver fibrosis was not evident in the short term.

Keyphrases

liver fibrosis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
antiretroviral therapy
oxidative stress
prognostic factors
peritoneal dialysis
patient reported outcomes