Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma.

Hao ZhanJiahao JiangQiman SunAiwu KeJinwu HuZhiqiang HuKai ZhuChubin LuoNing RenJia FanJian ZhouXiaowu Huang

Published in: Gastroenterology research and practice (2017)

This study reveals a mutational profile and a distinct mutation signature of T:A>A:T transversion in early-stage HCC with HBV infection, which will enrich our understanding of genetic characteristics of the early-stage HCC.

Keyphrases

early stage
hepatitis b virus
liver failure
sentinel lymph node
single cell
genome wide
gene expression
dna methylation
radiation therapy