High prevalence of reduced fertility and use of assisted reproductive technology in a German cohort of patients with peripartum cardiomyopathy.
Tobias Jonathan PfefferManuel ListCordula SchippertBernd AuberMelanie Ricke-HochValeska Abou-MouligDominik BerlinerJohann BauersachsDenise Hilfiker-KleinerPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2022)
Subfertility occurred frequently among PPCM patients and was associated with increased age, hormonal disorders, higher twin pregnancy rate and high prevalence of pathogenic gene variants suggesting a causal relationship between subfertility and PPCM. Although this study found no evidence that the ART treatment per se increases the risk for PPCM or the risk for an adverse outcome, women with subfertility should be closely monitored for signs of peripartum heart failure.