Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
V Gangadhara N V PrasadSatyanarayana AchantaYathiraja Rao TammineniGopala Reddy AllaMadhava Rao ThirthamG Srinivasa RaoPublished in: European journal of drug metabolism and pharmacokinetics (2018)
The results suggest that MRP4 inhibition increases the systemic exposure of ciprofloxacin in both normal and inflammatory conditions.