Protective effects of silymarin in glioblastoma cancer cells through redox system regulation.

Sara Zarei ShandizBahareh ErfaniSeyed Isaac Hashemy

Published in: Molecular biology reports (2024)

Our findings suggest that silymarin may exert its cytotoxic and anticancer effects by enhancing the Nrf2/HO-1 pathway through antioxidant mechanisms in U-87 MG cells.

Keyphrases

oxidative stress
induced apoptosis
cell cycle arrest
pi k akt
anti inflammatory
signaling pathway
endoplasmic reticulum stress