Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis.

Yury Yu BorshchevSarkis M MinasianInessa Yu BurovenkoVictor Yu BorshchevEgor S ProtsakNatalia Yu SemenovaOlga V BorshchevaMichael M Galagudza

Published in: PloS one (2019)

TTC reduced infarct size in the healthy rats. However, this effect was reversed in the obese animals with CIC. Additionally, it was associated with specific changes in gut microbiota and significantly elevated levels of cytokines and LPS.

Keyphrases

adipose tissue
weight loss
metabolic syndrome
acute myocardial infarction
type diabetes
obese patients
inflammatory response
left ventricular
heart failure
acute coronary syndrome