A Multifunctional Nano-Delivery System Against Rheumatoid Arthritis by Combined Phototherapy, Hypoxia-Activated Chemotherapy, and RNA Interference.
Xiangyu LiShixin ZhangMiaomiao ZhangGe LiBo YangXinyue LuLesheng TengYouxin LiFengying SunPublished in: International journal of nanomedicine (2022)
Overall, these FA-functionalized, pH-responsive PFHNs/TM represent a promising platform for the co-delivery of chemical drugs and nucleic acids for the treatment of RA cooperating with NIR-induced phototherapy.
Keyphrases
- rheumatoid arthritis
- disease activity
- drug delivery
- diabetic rats
- ankylosing spondylitis
- drug induced
- high throughput
- endothelial cells
- interstitial lung disease
- quantum dots
- oxidative stress
- drug release
- fluorescence imaging
- high resolution
- nucleic acid
- replacement therapy
- molecularly imprinted
- rectal cancer
- metal organic framework
- single cell
- stress induced