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Inhibitors against New Delhi metallo-betalactamase-1 (NDM-1) and its variants endemic in Indian settings along with the laboratory functional gain mutant of NDM-1.

Nabeela FarhatAsad U Khan
Published in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2024)
This is the first time inhibitors were tested against different NDM natural variants which are endemic in Indian settings. Moreover, a functional gain laboratory mutant was also checked for their efficacies. We may propose these molecules for the pre-clinical trial to further translate.
Keyphrases
  • klebsiella pneumoniae
  • clinical trial
  • copy number
  • wild type
  • multidrug resistant
  • study protocol
  • double blind
  • dna methylation