Insertional translocation involving an additional nonchromothriptic chromosome in constitutional chromothripsis: Rule or exception?
Nehir Edibe KurtasLuciano XumerleUrsula GiussaniAlessandra PansaLaura CardarelliVeronica BertiniAngelo ValettoThomas LiehrMaria Clara BonagliaEdoardo ErrichielloMassimo DelledonneOrsetta ZuffardiPublished in: Molecular genetics & genomic medicine (2018)
Our findings show that (a) both simple and complex unbalanced rearrangements may result by the recombination of a cryptic parental balanced chromothripsis and that (b) insertional translocations are the spy of more complex rearrangements and not simply a three-breakpoint event.