Cortical projection neurons as a therapeutic target in multiple sclerosis.

Tatjana BeutelJulia DzimieraHannah Kapell Maren EngelhardtAchim GassLucas Schirmer

Published in: Expert opinion on therapeutic targets (2020)

Excitatory cortical projection neurons are an emerging therapeutic target in the treatment of progressive MS. Understanding neuron subtype-specific molecular pathologies and their exact spatial mapping will help establish starting points for the development of novel cell type-specific therapies and biomarkers in MS.

Keyphrases

multiple sclerosis
spinal cord
mass spectrometry
white matter
ms ms
image quality
high resolution
computed tomography
spinal cord injury
high density
magnetic resonance
replacement therapy