An ultrasensitive luteolin electrochemical sensor based on a glass carbon electrode modified using multi-walled carbon nanotube-supported hollow cobalt sulfide (CoSx) polyhedron/graphene quantum dot composites.
Li ZhangPengcheng ZhaoChenxi WangYilin WangYaqi YangYixi XieJunjie FeiPublished in: The Analyst (2022)
Luteolin (LU), belonging to the group of flavonoids with rich biological activities, has attracted considerable attention. Herein, a novel ultrasensitive LU electrochemical sensor based on hollow cobalt sulfide polyhedron-multi-walled carbon nanotube nanocomposites (CoSx-MWCNTs) and graphene quantum dots (GQDs) was proposed. The hollow CoSx polyhedrons derived from ZIF-67 showed excellent electrochemical sensing performance, which was attributed to the abundant surface active sites endowed by the special hollow structure. When detecting LU using the DPV model, the CoSx-MWCNTs/GQDs/GCE showed a linear range of 5 nM-2000 nM under optimal conditions, and the corresponding detection limit (LOD) was 1.2 nM (S/N = 3). In addition, the sensor exhibited satisfactory sensitivity and accuracy for detecting LU in real samples from Chrysanthemum extracts.
Keyphrases
- carbon nanotubes
- molecularly imprinted
- label free
- solid phase extraction
- gold nanoparticles
- quantum dots
- photodynamic therapy
- walled carbon nanotubes
- reduced graphene oxide
- metal organic framework
- working memory
- sensitive detection
- simultaneous determination
- highly efficient
- real time pcr
- mass spectrometry
- neural network
- electron transfer