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Visuospatial memory impairment as a potential neurocognitive marker to predict tau pathology in Alzheimer's continuum.

Eun Hyun SeoHo Jae LimHyung-Jun YoonKyu Yeong ChoiJang Jae LeeJun Young ParkSeong Hye ChoiHoowon KimByeong C KimKun Ho Lee
Published in: Alzheimer's research & therapy (2021)
It is crucial to identify sensitive cognitive measures that capture subtle cognitive impairment associated with underlying pathological changes. Preliminary findings from the current study might suggest that abnormal tau accumulation underlies episodic memory impairment, particularly visuospatial modality, in the AD continuum. Suggested models are potentially useful in predicting tau pathology, and might be utilized practically in the field.
Keyphrases
  • working memory
  • cerebrospinal fluid
  • cognitive impairment
  • bipolar disorder
  • cognitive decline