The Influence of Treatment with Ledipasvir/Sofosbuvir on Growth Parameters in Children and Adolescents with Chronic Hepatitis C.

Maria Pokorska-ŚpiewakAnna DobrzenieckaMagdalena Marczyńska

Published in: Viruses (2022)

Treatment with LDV/SOF in children with CHC (genotypes 1 and 4) did not negatively influence the patients' growth. However, higher baseline BMI z scores correlated with more advanced liver fibrosis and steatosis in children with CHC.

Keyphrases

liver fibrosis
end stage renal disease
young adults
ejection fraction
chronic kidney disease
hepatitis c virus
newly diagnosed
body mass index
insulin resistance
prognostic factors
metabolic syndrome
combination therapy
weight loss