Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells.
Alicja SznarkowskaAnna KosteckaAnna KawiakPilar AcedoMattia LionAlberto IngaJoanna E Zawacka-PankauPublished in: Cell division (2018)
Our findings may in future contribute to the successful repurposing of PpIX into clinical practice.