HPLC Analytical Method Development and Validation of Gabapentin through Chemical Derivatization with Catechol as a Chromophore.

Murad N Abualhasan Fairouz Shraim Hiba Alawni Saba Hamdan Hadeel Khaseeb

Published in: International journal of analytical chemistry (2022)

The developed method is simple and feasible with high sensitivity and selectivity. It can be applied in the analysis of gabapentin in different dosage forms and raw materials including active pharmaceutical ingredients (API). This research work can be continued in the future, and the developed method can be used for testing gabapentin in biological systems.

Keyphrases

neuropathic pain
ms ms
simultaneous determination
high performance liquid chromatography
tandem mass spectrometry
spinal cord
spinal cord injury
solid phase extraction
current status
gas chromatography mass spectrometry
ultra high performance liquid chromatography