Rapid monophasic HBsAg decline during nucleic-acid polymer-based therapy predicts functional cure.

Leeor Hershkovich Louis M ShekhtmanMichel BazinetVictor PânteaGheorge PlacintaScott J CotlerAndrew VaillantHarel Dahari

Published in: Hepatology communications (2023)

Functional cure was associated with a rapid monophasic HBsAg decline during NAP-based therapy. A nonmonophasic HBsAg kinetic pattern had a 100% negative predictive value (NPV) for a functional cure.

Keyphrases

hepatitis b virus
nucleic acid
stem cells
loop mediated isothermal amplification
bone marrow