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A Phase II Trial of the Bruton Tyrosine-Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Relapsed/Refractory Waldenström Macroglobulinemia.

Gang AnDaobin ZhouShu ChengKeshu ZhouJianyong LiJian-Feng ZhouLiping XieJie JinLiye ZhongLingzhi YanHaiyi GuoChenmu DuJinhua ZhongYiling YuBinghao WuLugui Qiu
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Zanubrutinib achieved a high rate of response that was durable and deep in patients with R/R WM across all subgroups, and potentially confers a positive benefit-risk profile for WM.
Keyphrases
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • diffuse large b cell lymphoma
  • multiple myeloma
  • hodgkin lymphoma
  • open label
  • double blind